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Used to get 2-3 weekly migraines before Topamax and would run out of Fioricet and Imitrex. I tapered up to the 100 mg dose and while I do get the occasional tingling in my fingers and toes, its nothing compared to a full fledged migraine. I also dropped 8 or 9 lbs, which is a lot for me since I'm 5'2 and was 129, now I'm 121lbs. I have almost no appetite, but almost no migraines.
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XR (topiramate) Extended-Release Capsules is a prescription medicine used to treat certain types of seizures (partial-onset seizures and primary generalized tonic-clonic seizures) and with other medicines to treat certain types of seizures (partial-onset seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome) in adults and children 2 years and older.
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Breese CR, Freedman R, Leonard SS: Glutamate receptor subtype expression in the human post-mortem brain tissue from schizophrenic and alcohol abusers.
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