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Iressa is thought to inhibit the intra-cellular phosphorylation of tyrosine kinases associated with transmembrane cell surface receptors, including the tyrosine kinases associated with the epidermal growth factor receptor (EGFR-TK).

Other lung cancers (usually small cell cancer) cause the body to retain water, lowering the blood's sodium levels.

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The ESMO aka European Society for Medical Oncology was the location where the results of the experimentation was announced.

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Immunotherapy may produce protracted cancer remissions with high quality of life.

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In Europe, the collaboration between AstraZeneca and QIAGEN has resulted in IRESSA becoming the first EGFR tyrosine kinase inhibitor to have a European label supporting the use of circulating tumour DNA (ctDNA) obtained from a blood sample, to be used for the assessment of EGFR mutation status in those patients where a tumour sample is not an option.

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